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Biggest risk?

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There's a very high chance of XX XX!

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No matter the dose,

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you should stop the medication at least 1 month,

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ideally 3 months, before trying to XX XX.

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Not feeling great today, PD?

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PD: I had medicine on an empty stomach earlier 
and now I feel all messed up.

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Wait!

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You took it on an empty stomach?

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Didn't anyone warn you about that?

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PD: No, they did say to eat first...

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(Oh no...)

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You should've listened!

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Warnings exist for a reason!

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〈Acne Med Side Effects 1. Today's topic〉
Hello,

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[Jfeel clinic Chief Director Dr.Lee]
I'm Dr.Lee, here to help you look your best.

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When it comes to dermatology meds, especially acne meds,

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[Isn't it too harsh?]
they seem super harsh and bad for your body.

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So even when a prescription is needed,

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a lot say they don't want to take them.

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On the flip side,

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some people ask for prescription meds

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even when I don't thknk they really need them.

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So when should you take acne meds,

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and when should you be careful?

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Today, let's talk about the effects

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and side effects of oral acne medication.

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〈Acne Med Side Effects 2. How acne is treated〉
Acne is an inflammatory skin condition

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caused by clogged pores 
filled with oil and dead skin cells.

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Like any treatment,

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acne care also has its own steps.

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[No meds for just 1 or 2 pimples]
We don't prescribe acne medication

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just because you've got one or two small pimples.

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That's why treatment is done step by step.

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The first step is usually 
getting rid of the acne-causing bacteria,

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[So antibiotics come first]
which is why we start with antibiotics.

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Second, often dead skin cells bloking the pores,

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even more than excess oil.

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So we do exfoliation.

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[Clear out clogged pores!]
One of the most basic acne treatments is scaling.

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[Another treatment: Extraction!]
Third step is things like extraction.

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If there's too much oil,

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antibiotics aren't enough,

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so we use oil-suppressing meds.

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〈Acne Med Side Effects 3. Oral acne med〉
Early-stage acne is treated with oral antibiotics,

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while more severe cases are treated with isotretinoin.

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When it comes to antibiotics,

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we usually use things like doxycycline or minocycline.

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[How antibiotics work]
They block bacterial protein synthesis to fight infection,

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and because of its broad-spectrum antibacterial action,

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Doxycycline is often the first choice.

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Minocycline, with its stronger antibacterial effects,

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is considered a second-line option.

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But these days, more people
start with Minocin (minocycline).

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We usually

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prescribe antibiotics

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when someone has more than 10 red,

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inflamed pimples on their face.

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It's also better to take acne antibiotics for a longer period.

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At least 1 to 2 months, 
since they take time to work.

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The second option is an oil-control medication.

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Isotretinoin is commonly used

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and has a very strong oil-suppressing effect.

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A lot of people come in for it

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because they’re bothered by excessive oil

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or keep breaking out because of it.

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Since the effect builds up over time,

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it usually starts working after 2–3 weeks

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[Usually taken for 4 to 6 months]  
It's a long-term medication

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that's typically taken for about 4 to 6 months.

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PD: You said people take it long-term.

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PD: Won't it hurt the liver..?

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All meds affect the liver to some extent.

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And, of course, it’s worse if you drink while taking them.

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When taking any medication long-term,

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I usually tell patients to assume

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'It could put some strain on the liver'.

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Shh! Just between us!

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〈Acne Med Side Effects 4. Side Effects of Antibiotics〉
Let’s go over some common side effects of antibiotics.

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Like our PD here, people often experience

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heartburn, nausea, or stomach discomfort.

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Kids under 8 shouldn’t take them

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because they can cause tooth discoloration.

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Since they can affect the baby’s 
teeth and bone development,

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[Not for pregnant women!]
they're also off-limits during pregnancy.

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[Watch out for photosensitivity! Sunscreen is a must]
These meds can make your skin more sensitive to sunlight,

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so make sure to wear sunscreen.

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Minocycline has

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stronger antibacterial effects,

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but that also means stronger side effects

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[Watch out for dizziness]
like dizziness.

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[Possible skin discoloration with long-term use]  
Long-term use may sometimes cause skin discoloration.

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〈Acne Med Side Effects 4. Sebum suppressants〉
Isotretinoin, reduces sebum production.

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As for the side effects,

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common side effects include

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dry lips, dry mouth, dry skin, and dry eyes.

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The dryness can even lead to nosebleeds or cheilitis.

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Most of these go away once you stop taking the meds.

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Biggest risk?

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There's a very high chance of birth defects.

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According to public health guidelines, we must inform patients

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about the risk of birth defects before prescribing.

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No matter the dose,

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you should stop the medication at least 1 month,

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[Plan pregnancy after stopping the meds]
ideally 3 months, before trying to get pregnant.

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Also, blood donation is not allowed

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because your blood could be given to a pregnant woman.

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It’s approved for ages 12 and up,

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but since it may interfere with bone growth,

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it should be used with caution in growing children.

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[Rare, but hair loss is possible too]
There are reports that it affects the scalp and causes hair loss.

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[Isotretinoin is a vitamin A derivative]
Since it’s a derivative of Vitamin A,

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[Don't take it with vitamin A]
it’s not recommended to take it alongside Vitamin A supplements.

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It can raise cholesterol and triglyceride levels,

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so people with high cholesterol or a family history of it

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should be especially careful while taking this medication.

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Despite the side effects,

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it’s often the only option for people

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with excessive sebum production.

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The original brand is no longer on the market,

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and in Korea, patients are 
currently taking generic versions.

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PD: Can you take antibiotics and sebum suppressants together?

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Nope.

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You should never take them together.

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Everyone, if you’ve got both antibiotics 
and a sebum suppressant at home,

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even if your acne’s really bad,

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don’t take them together!

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〈Acne Med Side Effects 5. Effects on acne scars〉
A common routine prescription is

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Isotretinoin + Clindamycin-T (a topical antibiotic).

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In theory, it sounds like a great combo.

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But depending on the patient,

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it can dry out the skin.

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What happens when it gets dry?

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It can lead to scarring, and it doesn’t heal as well.

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While it reduces sebum production,

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[Bad for acne scars]
it can have a negative impact on acne scarring.

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So if you’re getting needle RF treatments

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[POTENZA, Secret]
like Potenza or Secret to improve acne scars,

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keep in mind that they’re strongly discouraged

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[Potenza/Secret scar laser is considered taboo]
while you’re on isotretinoin

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because it seriously hinders your skin’s ability to heal.

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So please make sure to keep that in mind.

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Instead of constantly relying on isotretinoin,

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I’d suggest considering a treatment

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[What about Agnes laser?]
that reduces the sebaceous glands themselves.

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So, how was today’s deep dive into acne meds?

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As with any medication, side effects are inevitable.

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If there’s one tip, it’s to stick with one clinic

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and work closely with your doctor

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to adjust your prescription as your acne progresses.

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[Subscribe to JFeel TV]
If you found this video helpful,

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don’t forget to like, subscribe, 
and turn on notifications.

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Thanks for watching.

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You'll all look more beautiful.

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